I worked as a lawyer with my dad for several years, then found myself drawn to my original love of science and became a science teacher. Ohio Republican Jim Jordan is incensed about Department of Transportation Secretary Pete Buttigieg's response to a train derailment in his state. We completed a combined examination of all three branches of adaptive immunity at the level of SARS-CoV-2-specific CD4+and CD8+Tcell and neutralizing antibody responses in acute and convalescent subjects. These researchers applied a registry-based study design that indeed lacks the level of precision of a test-negative design. 2 months after infection, which is consistent with longer-term protection., This super antibody for COVID fights off multiple coronaviruses12 antibodiesthat was involved in the study, isolated from people who had been infected with either SARS-CoV-2 or its close relative SARS-CoV., Taken together, our data indicate sustained humoral immunity in recovered patients who suffer from symptomatic COVID-19, suggesting prolonged immunity., Whereas anti-CoV-2 IgA antibodies rapidly decayed, IgG antibodies remained relatively stable up to 115 days PSO in both biofluids. A former Trump campaign official, Caputo has no science background but is now undersecretary for communications at the U.S. Health and Human Services department. He was brought in as a scientific adviser to Michael Caputo, a former Trump campaign staffer with no scientific or medical background installed as HHSs assistant secretary of public affairs in April. Alexander COVID News-Dr. Paul Elias Alexander's Newsletter is a reader-supported publication. Pradia; Prekiniai enklai Prekiniai enklai . Diese Liste umfasst alle Knstler, die bei den unterschiedlichen Ausgaben des CTM Festivals aufgetreten sind. To receive new posts and support my work, consider becoming a free or paid subscriber. Alexander COVID News-Dr. Paul Elias Alexander's Newsletter, COVID-19 and SARS-CoV-2: natural immunity; innate immunity; vaccines and immune pressure; no vaccines for children; early outpatient treatment; lockdowns; school closures and mask mandates and vaccine mandates and emergency powers and truck convoy, This site requires JavaScript to run correctly. Notably, these antibody responses were associated with virus-neutralizing activity that was still detectable 4 months after acute infection in 94% of children. Paul E. Alexander received his bachelor's degree in epidemiology from McMaster University in Hamilton, Ontario, a master's degree from Oxford University, and a PhD from McMaster University's Department of Health Research Methods, Evidence, and Impact. Share this post. But one respected expert who knows him suggests the CV doesnt tell the whole story. We are sorry. We further demonstrate experimentally that some memory T-cell immunity against S-OIV is present in the adult population and that such memory is of similar magnitude as the pre-existing memory against seasonal H1N1 influenza. Alexander holds master's level study at York University Canada, a master's in epidemiology at the University of Toronto, a master's in evidence-based medicine at Oxford and a doctorate in evidence-based medicine and research methods from McMaster University in Canada. They found that Effectiveness of only prior infection against symptomatic BA.2 infection was 46.1% (95% CI: 39.5-51.9%). The missives were sent by Paul Alexander, a part-time professor at Canadas McMaster University, an institution lauded worldwide for its dedication to the highest standards in medical research. Some were directed to the National Institutes of Health (NIH), suggesting what Dr. Anthony Fauci, the legendary head of the institutes infectious-disease division, should say in media interviews. Now I get to teach science during the day and write about it at night. And his allies have called for new COVID-19 treatments to be approved using lower-quality studies than randomized control trials. He has a master's in epidemiology from University of Toronto, and a master's degree from Oxford University. Issues relating to the arbitrability of disputes have gained increasing prominence in recent years. MEAWW brings you the best content from its global team of Dr. Alexander holds masters level study from York University Canada, and a masters in epidemiology from the University of Toronto, a masters in evidence-based medicine from the University of. A must read. Full content visible, double tap to read brief content. eventAction: 'click_adunit' However, the effect was larger in the first 14-59 days after complete vaccination compared to 60 days. 140 Research Studies Affirm Naturally Acquired Immunity to Covid-19: Documented, Linked, and Quoted. . Scientists may have different approaches or views on issues. The writer called for changes to those reports and appears to be a key force in the internal lobbying. evaluated the protection conferred by mRNA vaccines and previous infection against infection with the omicron variant in two high-risk populations; See Table S4 in supplementary for the important findings, there are zero (0) deaths in the unvaccinated (prior infected) and zero (0) deaths in the vaccinated; the study attempts to champion the vaccine yet the real finding is that there were no deaths on those unvaccinated in a closed high-risk prison population; these prisoners withstood death with their own immunity (natural immunity) and needed no vaccine, Researchers sought to evaluate dynamics of antibody levels following exposure to SARS-CoV-2 during 12 months in Dutch non-vaccinated hairdressers and hospitality staff., Dr. Harvey Risch, MD, PhD (YaleSchool of Public Health), Dr. Howard Tenenbaum, PhD (Faculty of Medicine, University of Toronto), Dr.Ramin Oskoui, MD (Foxhall Cardiology,Washington), Dr. Peter McCullough, MD (Truth for Health Foundation (TFH)), Texas, Dr. Parvez Dara, MD (consultant,Medical Hematologist and Oncologist). Dr. Alexander's tale of 2 dichotomies are profoundly informative and frightening at the same time. }); Did the Trump administration push for herd immunity? Texas Lindsay, This site requires JavaScript to run correctly. Read more about cookies here. Yet as they rightly argue, the very large number of cases studied that covered all the residents of Portugal over 12 years old, allowed confidence in a derived risk estimate for individuals with prior BA.1/BA.2 infection that was robust and trustworthy enough and located close to an estimate from Qatar based on a test-negative design. The revelations have been all over American news outlets in recent days: Trump White House appointees have repeatedly tried to control COVID-19 messaging from the respected Centers for Disease Control. The researchers conducted 6 national, matched, test-negative case-control studies were conducted to examine effectiveness of BNT162b2 (Pfizer-BioNTech) vaccine, mRNA-1273 (Moderna) vaccine, natural immunity due to prior infection with pre-Omicron variants, and hybrid immunity from prior infection and vaccination. No BS here! Kent Heckenlively, JD, is an attorney, science teacher, and New York Times bestselling author. }); But after Mr. Caputo joined HHS, his office began demanding the ability to make changes to the documents. Please use a different way to share. Bring your club to Amazon Book Clubs, start a new book club and invite your friends to join, or find a club thats right for you for free. Dr. Alexander said there might have been one or two times that the CDC changed its reports because of him, but he said he cant remember exactly what the changes were. A typical entry lists information in the following sequence: Name, age, country of citizenship at birth, subsequent country of citizenship (if applicable), reason for notability, cause of death (if known), and reference. Click this link for the original source of this article. 31. Moreover, the magnitude of Omicron cross-reactive T cells was similar to that of the Beta and Delta variants, despite Omicron harbouring considerably more mutations. Epidemiologist and former Covid advisor for the U.S. Department of Health and Human Services Dr. Paul Alexander. It must be difficult for [CDC] to be criticized by an Oxford-educated scientist who has been published in peer-reviewed journals 67 times.. Paul Alexander a part-time professor of health research methods, evidence and impact at McMaster since 2015 moved from Hamilton to Washington, D.C., in late March to advise a leading . Within the administration, Alexander advocated for a strategy of mass infection of the public with COVID-19 to build herd immunity. He earned his PhD from McMaster's Department of Health Research Methods, Evidence, and Impact. hitType: 'event', feb 27/lbma/otc options expiry tomorrow: gold closed up $6.95 to $1817.40//silver closed down 15 cents to $20.69//platinum closed up $1.95 to $942.95//palladium closed down $6.25 to $1430.45//covid updates: dr paul alexander/dr panda//vaccine impact//slay news//updates on the east palestine disaster//updates on the ukraine russia war: ukraine wants to lead an offensive to retake crimea//russia . However, the effect was larger in the first 14-59 days after complete vaccination compared to 60 days and longer. The employee could keep a job and not go into depths of despair and drink and commit suicide, he said. Vehemently, Alexander wrote Aug. 27, reported Politico. Best Buy, Fable and DAVIDsTEA, to name a few. This greater binding breadth means that single RBD mutations have less impact on neutralization by vaccine sera compared to convalescent sera. A call to action. 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Our greatest fears have now seemed to materialize. Chen et al. I read about a decade ago that the U.S. and European nations were being run by unelected bureaucrats in government departments that the elected politicians could not control, because they can't be fired and do whatever they decide should be done. , has expertise in teaching of epidemiology (clinical epidemiology), evidence-based medicine, and research methodology. Alexander COVID News-Dr. Paul Elias Alexander's Newsletter is a reader-supported publication. ga('create', 'UA-67136960-15', 'auto', 'ads'); He will let you know what we all should know now from the point of view of hard science. It is known that cross-reactive T-cell immune responses can exist even between serologically distinct influenza A strains (, Observe higher frequencies of cross-reactive (p=0.0139), and nucleocapsid-specific (p=0.0355) IL-2-secreting memory T cells in contacts who remained PCR-negative despite exposure (n=26), when compared with those who convert to PCR-positive (n=26); no significant difference in the frequency of responses to spike is observed, hinting at a limited protective function of spike-cross-reactive T cells. A former associate at McMaster suggested Paul Alexander had fallen under the sway of Michael Caputo, the ardent Trump loyalist who is his current boss. Therefore, children generate robust, cross-reactive and sustained immune responses to SARS-CoV-2 with focused specificity for the spike protein. We would like to show you a description here but the site won't allow us. A man with only truth as his weapon, and with very few teammates, tries to take on the Goliath of D.C. corruption and politics. Alexander is a Candian health researcher who garnered immense attention for his response to the Covid-19 pandemic while serving as an aide to HHS assistant secretary for public affairs Michael Caputo under the Trump administration. Pope Alexander III. A parsimonious explanation is that coordinated CD4+Tcell, CD8+Tcell, and antibody responses are protective, but uncoordinated responses frequently fail to control disease, with a connection between aging and impaired adaptive immune responses to SARS-CoV-2., Protection from reinfection decreases with time since previous infection, but is, nevertheless, higher than that conferred by vaccination with two doses at a similar time since the last immunity-conferring event., The protective effect of prior SARS-CoV-2 infection on re-infection is high and similar to the protective effect of vaccination., Compare SARS-CoV-2 spike receptor binding domain (S1-RBD)-specific primary MBCs that form in response to infection or a single mRNA vaccination. I continue to have an issue with kids getting tested and repeatedly and even university students in a widespread mannerand I disagree with Dr. Fauci on this. ga('ads.send', { Very misleading by CDC and shame on them., Dr. Srinivas Murthy, who is co-heading the Canadian branch of the World Health Organizations clinical trials on various potential COVID-19 treatments, said he was especially disturbed at the attempts to line edit the weekly reports, which everyone around the world listens to and looks to., It surprises me that anyone who claims to be in the interest of research and transparency would make statements like that, said the University of British Columbia professor. He has been a controversial figure in general for his intervention in COVID work by U.S. agencies. if(document.querySelector("#google_image_div")){ In an email sent on July 4, Paul Elias Alexander, an advisor to Health and Human Services Assistant Secretary for Public Affairs Michael Caputo, said that the administration should open businesses . MEAWW is an initialism for Media Entertainment Arts WorldWide. His books have sold more than a quarter of a million copies and have been translated into several languages. Importantly, IgG responses in saliva and serum were correlated, suggesting that antibodies in the saliva may serve as a surrogate measure of systemic immunity., Early appearance, multi-specificity and functionality of SARS-CoV-2-specific T cells are associated with accelerated viral clearance and with protection from severe COVID-19., Found a significantly faster decay in nave vaccinees compared to recovered patients suggesting that the serological memory following natural infection is more robust compared to vaccination. The Alexander's have two grown children. I fully understand what Im saying, and that 99% of people either cant leave, or want to wait for more information, or just generally refuse to believe something of this scale could ever happen here. hitType: 'event', Please. Dr. Paul E. Alexander, PhD, has expertise in teaching of epidemiology (clinical epidemiology), evidence-based medicine, and research methodology. The development comes after Politico and the Washington Post published a string of e-mails from Dr. Alexander and Mr. Caputo attempting to silence scientists working on COVID-19 or make them change their reports to downplay the pandemics severity and support Mr. Trumps messaging. We ask you to keep your comments relevant and respectful. When it is present it may be a signal of steroid-responsiveness.Alexander COVID News-Dr. Follow authors to get new release updates, plus improved recommendations. Dr. Alexander would not discuss his relationship with Mr. Caputo. Researchers studied the duration of protection afforded by natural infection, the effect of viral immune evasion on duration of protection, and protection against severe reinfection, in Qatar, between February 28, 2020 and June 5, 2022. A few internal emails obtained by the House Oversight Committees coronavirus select subcommittee have revealed that Donald Trump appointee Paul Alexander, who previously served at the US Department of Health and Human Services, wanted all Americans infected with the deadly Covid-19 virus. Dr. Paul Alexander was a guest on the Clay and Buck Show describing his research into why 'children should not be vaxxed' for Covid-19. }); . The question of which law ought to govern an arbitration agreement and concomitantly the inquiry as to whether a dispute is arbitrable, in the absence of an explicit choice of law governing the arbitration agreement has been explored in previous judgments. Moreover, antibody responses and neutralizing activity in sera from children and adolescents were comparable or superior to those observed in sera from 24 adults with mild symptomatic infection. Who is Paul Alexander? To assess robustness of mRNA vaccine-induced immunitycompared antibody durability and breadth after SARS-CoV-2 infection and vaccinationWhile vaccination delivered robust initial virus-specific antibodies with some cross-variant coverage, pre-variant SARS-CoV-2 infection-induced antibodies, while modest in magnitude, showed highly stable long-term antibody dynamicsDifferential antibody durability trajectories favored COVID-19-recovered subjects with dual memory B cell features of greater early antibody somatic mutation and cross-coronavirus reactivityilluminating an infection-mediated antibody breadth advantage and an anti-SARS-CoV-2 antibody durability-enhancing function conferred by recalled immunity., Compare antibody and cellular immunity in children (aged 3-11 years) and adults. The following is a list of notable deaths in December 2018 . These results are consistent with reports about disease incidence, severity, and mortality rates associated with human S-OIVoverall, 49% of the epitopes reported in the literature and present in recently circulating seasonal H1N1 are also found totally conserved in S-OIV. There was an error, please provide a valid email address. Reviewed in the United States on February 8, 2023. Effectiveness of only two-dose BNT162b2 vaccination was negligible at -1.1% (95% CI: -7.1-4.6), but nearly all individuals had received their second dose several months earlier. Canadian professor at heart of controversy over White House push to control COVID-19 messaging, Trudeau was regularly briefed on foreign interference in elections, national security adviser says, Michael Higgins: 'A lot of reason to be afraid,' says censured teacher critical of the woke revolution in classrooms, John Ivison: Whether the Liberals winked at Chinas helpful election meddling is the lingering question, Latest border-crossing crisis for U.S.: a potential flood of Canadian 'super pigs', U.S. company that made deal to produce COVID vaccine in Canada warns it could go out of business. Dr. Alexander said that he is originally from the Caribbean and has legal status in the U.S., but "Canada is my home" and "the greatest nation in the world." He received his PhD in health. Paul passed away in month 1972, at age 48 at death place. Reviewed in the United States on December 6, 2022. Paul Elias Alexander, an assistant professor of health-research methods at the Hamilton university, joined the U.S. Department of Health and Human Services earlier this year. Alexander COVID News-Dr. Paul Elias Alexander's Newsletter is a reader-supported publication. eventAction: 'click_image_ads' Please. He worked/was appointed in 2008 at WHO as a Regional Specialist/Epidemiologist in Europes Regional Office in Denmark (nations assigned in WHOs project were Russia, Turkey, Ukraine, and Poland). To see McMaster associated with this kind of advice just took me by surprise.. Antibody responses against spike protein were high in children and seroconversion boosted responses against seasonal Beta-coronaviruses through cross-recognition of the S2 domain. Spike-specific responses were also broadly stable beyond 12 months. Subscribe Sign in. He is a former professor at McMaster University in evidence-based medicine; former COVID pandemic advisor to WHO-PAHO in Washington, D.C. (2020); and a former senior advisor on COVID pandemic. Effectiveness of hybrid immunity of prior infection and two-dose BNT162b2 vaccination was 55.1% (95% CI: 50.9-58.9%). The key finding was There are no discernable differences in the effects of prior infection, vaccination, and hybrid immunity against BA.1 versus BA.2.. We analyzed 28,578 sequenced SARS-CoV-2 samples from individuals with known immune status obtained through national community testing in the Netherlands from March to August 2021. Politico first broke the stories revolving around Alexander, quoting emails from him that the news site had obtained. Dr. Alexanders positions in these e-mails largely contradict scientific consensus and back Mr. Trump. Menu. eventAction: 'view' }); An explosive behind-the-scenes look at Donald Trump's final months in office and how the COVID crisis response was a carefully crafted plan to ruin him.In January 2020, Donald Trump was on the fast track to an easy re-election. 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