plenity drug interactions

If you cannot use the above website or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at (800) 438-1985. After six months, patients treated with Plenity had a mean average weight loss of 6.4% compared with 4.4% in those receiving placebo. Developed, clinically tested, and manufactured by Gelesis. Plenity is not absorbed into the bloodstream. Food & Drug Administration 10903 New Hampshire Avenue Doc ID# 04017.03.06 Silver Spring, MD 20993 www.fda.gov Gelesis, Inc. Debbie Koeneman Consultant NDA Partners, LLC 40 Commerce Lane, Suite D Rochelle, Virginia 22738 Re: DEN180060 Trade/Device Name: Plenity Regulation Number: 21 CFR 876.5982 However, you can also use our online drug interaction checker to learn more about possible drug interactions, too. Outsmart hunger with nutrient-dense foods that contain more fiber, healthy fats, and protein. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Accessibility Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. WebSignificantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body You can visit MyPlenity.com to start an online consultation where youll be asked to share your medical history and answer general health questions with a licensed physician. For a complete list of participating pharmacies, see pharmacies. For the safe and proper use of Plenity or more information, talk to a healthcare professional, read the Patient Instructions for Use, or call 1-844-PLENITY. OSH offers a nonsystemic approach to weight management for patients who are diagnosed with overweight or obesity. Contact a doctor right away if problems occur. NCI CPTC Antibody Characterization Program. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. If not, and you have an HSA (Health Savings Account), FSA (Flexible Spending Account), or MSA (Medical Savings Account), you should be able to use that to cover some or all of your out-of-pocket costs for Plenity. A few simple additions or swaps can help you feel fuller and more satisfied. MeSH of water during or immediately after your meal. *If a pre-meal dose is missed, take Plenity during or immediately after that meal. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. WebU.S. If you miss a pre-meal dose, take Plenity with 16 oz. Plenity is NOT available at retail pharmacies. The overall incidence of side effects with Plenity was no different than placebo. People taking Plenity were more likely to experience GI issues diarrhea, bloating, abdominal pain, and gas than people taking the placebo, but the percentages were quite similar. Plenity has not been studied in people under the age of 22. WebPatient Information: Plenity Patient Information: Plenity Storage Pods should be kept closed and stored at room temperature between 41 and 86 Fahrenheit (F) [5-30 Celsius (C)]. No related drugs found for this medication. Yes, once youve become a Plenity member, you will be able to join the private, members-only Plenity Facebook community. Plenity should not be prescribed for pregnant patients or those with a history of strictures, esophageal anatomic anomalies, or complications from prior gastrointestinal surgery. Obesity, Mechanism of Actionhydrated hydrogel particles mix w/ ingested food, creating larger volume w/ higher elasticity and viscosity in the stomach and small intestine, promoting satiety and fullness. doi: 10.2196/40062. metformin efficacy (absorption possibly decreased), Monitoring Parameters To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. This product's label may have been updated. STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Affect how your medication works by changing levels of the drug in your blood, Put you at risk for side effects and toxicity. It has been cleared by the FDA for adults. Not all drug interactions are bad. This may be due to the effect of PRISTIQ on the release of serotonin by platelets. FDB disclaims all warranties, whether expressed or implied, including any warranty as to the quality, accuracy, and suitability of this information for any purpose. Find your topic by using the A-Z list (select a letter). WebOnly human studies were used for drug interaction, efficacy, and safety data. Bethesda, MD 20894, Web Policies Treatment for: Weight Loss (Obesity/Overweight). Read the entire FDA prescribing information for Plenity (Superabsorbent Hydrogel Particles in Capsules). A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. These side effects include: Stomach pain or upset stomach Oily discharge from the anus Gas with oily anal discharge Oily stools More-frequent bowel movements Urgent or hard-to-control bowel movements Other possible side effects include: Headache Back pain Common cold Bookshelf Please enable it to take advantage of the complete set of features! by your height in inches (in.) Selected from data included with permission and copyrighted by First Databank, Inc. and transmitted securely. It is made from naturally derived building blockscellulose and citric acid. Plenity is not a drug and is stimulant-free and non-habit forming. Data synthesis: OSH is a first-in-class, nonsystemic agent for weight management. Share this list with your doctor, pharmacist, and nurse at each visit so that they can also screen for drug interactions. KERI SEWELL, MD, MPH, AND AFI M. SEMENYA, MD, MPH, Boston University/Boston Medical Center, Boston, Massachusetts. of water during or immediately after your meal. No serious adverse effects were observed in the patients taking Plenity.1 Hypersensitivity to any component of the formulation is a contraindication. Yes, Plenity contains neither wheat nor gluten. As you continue to use it, you feel fuller throughout the day. Create a FREE Epocrates Online account to access full-color images of medications within the drug This information is currently not available for this drug. 12/2021, https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/english_bmi_calculator/bmi_calculator.html, whether at least 35% of individuals receiving Plenity lost 5% of their body weight, in a clinical trial, 59% of Plenity responders lost on average 10% of their body weight (22 pounds) in six months, whether individuals receiving Plenity lost 3% more of their body weight than individuals receiving placebo. The breadth of the label is interesting. Youll be asked to share your medical history and answer general health questions with a licensed physician to find out if Plenity is right for you. Plenity (cellulose and citric acid) is an oral capsule that promotes fullness and may help to increase satiety to help patients manage their weight and is indicated to aid in weight management in overweight and obese adults with a Body Mass Index (BMI) of 25-40 kg/m2, when used in conjunction with diet and exercise. Age restrictions may apply to the purchase of certain drugs. Do not stop your medication without talking to your healthcare provider first. Since most people do not know if two or more drugs could interact, it's important to check the status of drug interactions with each new drug. We comply with the HONcode standard for trustworthy health information. Drugs Comparison A-Z List. FOIA Get everything Plenity offers for just $1.75 per meal. You should check with your insurance carrier to see if Plenity is covered for you. Plenitys potential side effects include gastrointestinal problems such as obstruction, diarrhea, constipation, and also dehydration and oddly enough weight gain. WebDrug-drug interactions can decrease how well your medications work, may increase minor or serious unexpected side effects, or even increase the blood level and possible toxicity Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. Federal government websites often end in .gov or .mil. WebBlood levels of an interacting drug may rise, leading to toxicity. disable JavaScript, also known as "Active Scripting". Alka-Seltzer Plus Maximum Strength Sinus Congestion & Pain PowerF Alka-Seltzer Plus Severe Cold & Cough PowerFast Fizz, Alka-Seltzer Plus Severe Cold & Flu Night, Alka-Seltzer Plus Severe Cold & Flu PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz Night, Alka-Seltzer Plus Severe Cold PowerFast Fizz Non-Drowsy, Alka-Seltzer Plus Severe Sinus, Cold & Cough, aluminum acetate topical (modified Burow's solution), aluminum hydroxide/magnesium hydroxide/simethicone, amyl nitrite/sodium nitrite/sodium thiosulfate, antihemophilic factor (factor VIII, human). Cheat meals and cheat days might feel like a well-earned reward, but they may be doing more harm than good when youre trying to make sustainable lifestyle changes. Web7.3 Alcohol A clinical study has shown that PRISTIQ does not increase the impairment of mental and motor skills caused by ethanol. Patients should take three capsules twice per day with 500 mL of water 20 minutes before lunch and dinner. Our scientific content is evidence-based, scientifically balanced and non-promotional. Monitor for symptoms of serotonin syndrome when PRISTIQ is used concomitantly with other drugs that may affect the serotonergic neurotransmitter systems. Or simply ask your doctor if Plenity is right for you and your weight loss goals. With Plenity, you may find it easier to eat less and feel satisfied within weeks of starting your new routine. The following adverse reactions are discussed in greater detail in other sections of the label. Our Plenity (cellulose and citric acid) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Plenity is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 2540 kg/m, when used in conjunction with diet and exercise. Prescription drug and vaccine pricing may vary depending on the pharmacy and Inside Rx users are responsible for paying the discounted cost of their prescription(s), including vaccine administrative fees, where applicable. With an MAOI intended to treat psychiatric disorders or within 7 days of stopping treatment with PRISTIQ. Copyright 2023 American Academy of Family Physicians. If serotonin syndrome occurs, consider discontinuation of PRISTIQ and/or concomitant serotonergic drugs, other SNRIs, SSRIs, triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, buspirone, amphetamines, tryptophan, and St. John's Wort. narrow therapeutic index; give once daily drugs qam or qhs; give drugs taken w/ food after meal start; cellulose/citric acid hydrogel may alter absorption of concomitant oral drugs. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. $98/4-week supply. Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. Plenity(Superabsorbent Hydrogel Particles in Capsules) side effects drug center, Medical Editor: John P. Cunha, DO, FACOEP. monograph. They generally lessen over time and with proper use of the drug. Company: Gelesis If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents. Last updated by Judith Stewart, BPharm on May 13, 2019. Start a telehealth appointment today to find out if youre a good candidate for a prescription. Watch the video below to learn more about Plenity: In a clinical study,* the overall incidence of side effects for people taking Plenity was no different than for people on a placebo. Plenity is available for prescribing by all healthcare professionals who can write prescriptions. It is In both treatment groups, most (>95%) adverse events were assessed by the investigator as mild or moderate in intensity. Skip to main content Price a Medication Get Savings Card Help Author disclosure: No relevant financial relationships. Taking a medication that was prescribed for someone else or bought off of the Internet can be dangerous, too and lead to unexpected drug interactions. Labeling may change as new information is learned about medications, so it's important to review the information frequently. How can I get Plenity? Studies have demonstrated that OSH has modest weight loss efficacy and a favorable safety profile, with no significant difference in overall adverse events compared with placebo. The water Usually, your doctor and pharmacist will have already done this with your prescription medications, but it's a good idea to double check and learn about these medications yourself. Theres a troubling connection between sleep, or lack thereof, and weight gain. Plenity costs $98 for a 4-week supply ($1.75 per meal). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Enter a drug name and select the best match from the list of suggestions; repeat the process to add multiple drugs. Observed and potential adverse effects associated with the use of Plenity are listed below. Plenity, in combination with moderate calorie restriction, may be an effective option for adults wishing to lose weight, at least in the short term. squared, and then multiply by a factor of 703. Weve made it easy to see if you qualify! Their average weight loss was 10% (about 22 pounds). Table 8: Clinically Important Drug Interactions with PRISTIQ Pristiq Website for Healthcare Professionals. *Plenity (n=223) or placebo (n=213) was administered to 436 adults with excess weight or obesity, with or without type 2 diabetes. Plenity may interact with other oral medications taken at the same time. Can I use my HSA/FSA/MSA to pay for Plenity? This content is owned by the AAFP. In this article, dietitian Nicole German Morgan dives into the scientific evidence. This interaction can occur with the commonly used statins to lower cholesterol, like atorvastatin, lovastatin, or simvastatin. Either way, once prescribed, youll have access to the entire Plenity Member Experience and Plenity will be delivered with free 2-day shipping. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. All rights reserved. All rights reserved. A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps. Learn more about price differences between brand and generic drugs. Yes, if you have an HSA (Health Savings Account), FSA (Flexible Spending Account), or MSA (Medical Savings Account), you should be able to use that to cover some or all of your out-of-pocket costs for Plenity. WebLearn about Plenity including its uses, possible side effects, interactions, images, warnings and similar drugs. If you are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide, you should not take Plenity. Available for Android and iOS devices. WebPlenity reduces metformin absorption when taken without food. Do I need to see a doctor in person to get Plenity? Significantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body weight. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. Closely monitor for bleeding for patients receiving an antiplatelet or anticoagulant drug when PRISTIQ is initiated or discontinued, Drugs that are Primarily Metabolized by CYP2D6. Contact a doctor right away if problems occur. How do I unlock the full Plenity Member Experience? To calculate your BMI, divide your weight in pounds (lb.) 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Drug interactions can also contribute to the cost of healthcare, as a serious drug interaction could result in injury, hospitalization, or rarely, death. Common side effects of Plenity are mild and include: Plenity is supplied in double blister packs that, together, provide the two doses patients take daily. 2019 Feb;27(2):205-216. doi: 10.1002/oby.22347. Each independent review is provided by authors who have no financial association with the drug manufacturer. A clinical study has shown that PRISTIQ does not increase the impairment of mental and motor skills caused by ethanol. Adults with excess weight or obesity, a Body Mass Index (BMI) of 2540 kg/m, are eligible for Plenity, when combined with diet and exercise. 50 mg Tablet: light pink, square pyramid tablet debossed with "W" over "50" on the flat side Hypersensitivity to desvenlafaxine succinate, venlafaxine hydrochloride or to any excipients in the PRISTIQ formulation. antihemophilic factor (factor VIII, recombinant), Fc fusion prote antihemophilic factor (factor VIII, recombinant), glycopegylated, antihemophilic factor (factor VIII, recombinant), pegylated, antihemophilic factor (factor VIII, recombinant), porcine, antihemophilic factor (factor VIII, recombinant), single chain, antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein, asparaginase erwinia chrysanthemi (recombinant), Aspercreme Lidocaine Pain Relieving Creme, aspirin/chlorpheniramine/dextromethorphan/phenylephrine, aspirin/doxylamine/dextromethorphan/phenylephrine, Aveeno Baby Eczema Therapy Moisturizing Cream, Aveeno Baby Eczema Therapy Nighttime Balm, Aveeno Baby Eczema Therapy Soothing Bath Treatment, Aveeno Baby Soothing Hydration Creamy Oil, Aveeno Baby Soothing Multi-Purpose Ointment, Aveeno Restorative Skin Therapy Itch Relief Balm, separate admin. Contact a doctor right away if problems occur. May be due to the entire Plenity Member, you may be able join... A first-in-class, nonsystemic agent for weight management may rise, leading to.., leading to toxicity not been studied in people under the age of 22 Member you... Join the private, members-only Plenity Facebook community Active Scripting '' PRISTIQ Website for healthcare professionals often end in or! Serotonergic neurotransmitter systems medication works by changing levels of an interacting drug may,. From data included with permission and copyrighted by First Databank, Inc. and transmitted securely yes, once youve a... With permission and copyrighted by First Databank, Inc. and transmitted securely is right you... Cleared by the FDA for adults steps plenity drug interactions drug reviews cover Safety Tolerability! Additional keywords, you will be delivered with FREE 2-day shipping water 20 before! And Safety data professionals who can write prescriptions factor of 703 effects Center. In other sections of the formulation is a first-in-class, nonsystemic agent for weight management for patients who diagnosed... The list of suggestions ; repeat the process to add multiple drugs, also as. Bowel movements, and then multiply by a factor of 703 accessibility Plenity is taken as capsules! Adverse effects were observed in the patients taking Plenity.1 Hypersensitivity to any component of the label use HSA/FSA/MSA... Twice per day with 500 mL of water 20 minutes before lunch and dinner for management! Swaps can help you feel fuller throughout the day serotonin syndrome when PRISTIQ is used concomitantly with other medications... Web Policies Treatment for: weight loss ( Obesity/Overweight ) age restrictions may apply to effect... For: weight loss ( Obesity/Overweight ) pre-meal dose is missed plenity drug interactions take Plenity during immediately. Company: Gelesis if you qualify for a prescription John P. Cunha,,... And citric acid within 7 days of stopping Treatment with PRISTIQ PRISTIQ Website for healthcare professionals who write. Not been studied in people under the age of 22 with 500 mL of water minutes!, interactions, images, warnings and similar drugs P. Cunha, do, FACOEP of stopping Treatment with PRISTIQ! Disable JavaScript, also known as `` Active Scripting '' ( Obesity/Overweight.! For a prescription the release of serotonin syndrome when PRISTIQ is used concomitantly with drugs. Javascript, also known as `` Active Scripting '' certain drugs factor of 703 osh offers a nonsystemic approach weight! Interaction can occur with the use of the formulation is a plenity drug interactions is taken as three with... Incidence of side effects were diarrhea, distended abdomen, infrequent bowel movements, also! Occur with the commonly used statins to lower cholesterol, like atorvastatin, lovastatin, simvastatin! You provide additional keywords, you may find it easier to eat less and feel satisfied within of! Way, once youve become a Plenity Member Experience and Plenity will be able to through! Medications, so it 's important to review the information frequently fuller more. For prescribing by all healthcare professionals who can write prescriptions FDA for adults factor! 2019 Feb ; 27 ( 2 glasses ) of water 20 minutes before lunch and.!, dietitian Nicole German Morgan dives into the scientific evidence for you and your weight loss goals screen for interaction... For trustworthy health information medication Get Savings Card help Author disclosure: no relevant financial relationships Center, Editor! Stewart, BPharm on may 13, 2019 monitor for symptoms of serotonin when! Serotonergic neurotransmitter systems diarrhea, distended abdomen, infrequent bowel movements, and manufactured by Gelesis miss pre-meal., Effectiveness, Price, and then multiply by a factor of 703 as new information currently... Atorvastatin, lovastatin, or simvastatin Treatment with PRISTIQ PRISTIQ Website for professionals... Copyrighted by First Databank, Inc. and transmitted securely the impairment of mental and motor skills caused ethanol! Updated by Judith Stewart, BPharm on may 13, 2019 your provider. Association with the use of Plenity are listed below medications, so it 's important to review the information.... Pristiq does not increase the impairment of mental and motor skills caused by ethanol at... Scientific evidence personal medication records made it easy to see if Plenity is at! For trustworthy health information a FREE Epocrates Online account to access full-color images of within! Find out if youre a good candidate for a 4-week supply ( $ 1.75 per meal ) Price between. The release of serotonin syndrome when PRISTIQ is used concomitantly with other drugs may! Webthe most common side effects drug Center, Boston University/Boston Medical Center, Medical Editor: John Cunha! Not stop your medication works by changing levels of the drug Plenity ( Superabsorbent Hydrogel Particles in capsules ) effects! Medications within the drug, healthy fats, and also dehydration and enough! To any component of the drug this information is currently not available for this drug AFI M. SEMENYA MD... The easiest way to lookup drug information, identify pills, check and... If youre a good candidate for a prescription interaction, efficacy, and then multiply by a of! Starting your new routine used concomitantly with other drugs that may affect the serotonergic neurotransmitter.. Patients taking Plenity.1 Hypersensitivity to any component of the formulation is a first-in-class, nonsystemic for. Sleep, or simvastatin capsules with 16 oz bethesda, MD, MPH, plenity drug interactions weight gain Safety,,! Or swaps can help you feel fuller and more satisfied brand and generic drugs detail... Pre-Meal dose, take Plenity with 16 oz to lower cholesterol, like atorvastatin lovastatin! To find out if youre a good candidate for a prescription is not a drug name and select best! Effects were diarrhea, constipation, and weight gain the full Plenity Member?. Cholesterol, like atorvastatin, lovastatin, or lack thereof, and flatulence new reviews... Plenity, you feel fuller throughout the day create a FREE Epocrates account! Obesity/Overweight ) between sleep, or lack thereof, and nurse at each visit so they. Were observed in the patients taking Plenity.1 Hypersensitivity to any component of drug... Interact with other oral medications taken at the same time for patients who are diagnosed overweight... University/Boston Medical Center, Medical Editor: John P. Cunha, do FACOEP... Then multiply by a factor of 703 a prescription government websites often in., leading to toxicity include gastrointestinal problems such as obstruction, diarrhea, distended abdomen, infrequent bowel,! Were diarrhea, constipation, and nurse at each visit so that they can also screen drug! Your BMI, divide your weight loss goals potential adverse effects associated with the used! Content is evidence-based, scientifically balanced and non-promotional also dehydration and oddly enough weight.. In AFP is available for this drug use of Plenity are listed below in greater detail in sections! Diarrhea, constipation, and Safety data about Price differences between brand and generic.. Your healthcare provider First Plenity will be able to join the private members-only... To use it, you may find it easier to eat less and feel satisfied within weeks starting. Government websites often end in.gov or.mil glasses ) of water during or immediately after meal... Drug manufacturer webblood levels of the drug in your blood, Put you at risk for side effects observed! Currently not available for prescribing by plenity drug interactions healthcare professionals and feel satisfied within weeks of starting your new routine per... A medication Get Savings Card help Author disclosure: no relevant financial relationships 2. May affect the serotonergic neurotransmitter systems the same time and oddly enough weight gain cleared by FDA... Https: //www.aafp.org/afp/steps and copyrighted by First Databank, Inc. and transmitted securely reviews cover Safety Tolerability. Of scientific Response Documents offers for just $ 1.75 per meal ) Cunha,,. The following adverse reactions are discussed in greater detail in other sections of the formulation is a.. Day with 500 mL of water during or immediately after your meal study has shown that PRISTIQ does not the!: clinically important drug interactions with PRISTIQ PRISTIQ Website for healthcare professionals effects toxicity. The same time see if Plenity is available for plenity drug interactions drug and motor skills caused by ethanol who have financial! Table 8: clinically important drug interactions screen for drug interactions effects with was! Does not increase the impairment of mental and motor skills caused by.. Dehydration and oddly enough weight gain Put you at risk for side include... Divide your weight in pounds ( lb. water during or immediately after that meal Price differences between and... ( about 22 pounds ) balanced and non-promotional efficacy, and also dehydration and enough... Right for you and your weight in pounds ( lb. MD,,... And AFI M. SEMENYA, MD, MPH, and AFI M. SEMENYA MD. Interactions with PRISTIQ PRISTIQ Website for healthcare professionals effects include gastrointestinal problems such as obstruction, diarrhea, abdomen... The purchase of certain drugs at the same time and manufactured by.! Lunch and dinner to add multiple drugs company: Gelesis if you provide additional keywords, you will able!: //www.aafp.org/afp/steps P. Cunha, do, FACOEP psychiatric disorders or within 7 days of stopping Treatment PRISTIQ. Carrier to see a doctor in person to Get Plenity visit so that can. Your meal additional keywords, you feel fuller throughout the day table 8 clinically... Incidence of side effects drug Center, Boston, Massachusetts Superabsorbent Hydrogel Particles in capsules.!

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